Flower City AI 2026

The missing layer in your AI stack

Brian O'Keefe

Wednesday December 2, 2026 at The Little Theatre, Rochester, NY · 9:35AM-10:20AM

Most AI applications find information by similarity, which works well until a question depends on how things relate. Brian O'Keefe, Solutions Engineering Manager for the Neo4j Startup Program, will introduce graph databases to a general audience and explain how they store data as connected entities and relationships. He will show how graphs sit at the center of three of the hottest topics in AI: agentic memory, explainability, and GraphRAG.

Organizations across Rochester's healthcare, education, business, and research communities hold data where connections matter: patients and care pathways, courses and prerequisites, suppliers and products, studies and citations. When an AI system cannot see those connections, it returns plausible answers that it cannot explain. This session will make the case that connected data gives AI agents durable memory, gives users traceable answers, and gives retrieval the context that vector search alone lacks.

You will leave with a clear mental model of how graphs fit into an AI architecture and an understanding of where they improve accuracy, explainability, and reasoning. You will also take away a short list of use cases to evaluate in your own field. No prior experience with graph databases or AI development will be required.

About the speaker

Brian O'Keefe

Brian O'Keefe

Neo4j

Brian O'Keefe is the Solutions Engineering Manager for the Neo4j Startup Program. He helps AI startups design, launch, and scale on graph technology. Brian has more than two decades of experience in software architecture and research roles, including at major companies such as Thomson Reuters and Amazon Web Services....

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